… Abstract: MyristoylCoA:protein N-myristoyltransferase (NMT) catalyzes the … proteins. The
myristoyl moiety is often essential for expression of the biological functions for these proteins. …

… is catalysed by myristoyl-CoA:protein N-myristoyltransferase (NMT) a … Subsequently
peptidomimetic inhibitors entered the stage but they too … myristoyltransferase: a new approach to …

… to a functional peptide binding site and formation of a myristoylCoA:NMT:peptide ternary …
develop the first potent and species-selective peptidomimetic inhibitors of the acyltransferase. A …

… and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and
… ICM-a new method for protein modeling and design: applications to docking and structure …

… albicans Nmt, dipeptide inhibitors of the fungal enzyme have … of peptide substrates but not
myristoyl-CoA. Several potent … selectivity for peptidomimetic inhibitors of Candida albicans …

… A peptide substrate then binds to generate a myristoyl-CoA:… One is the peptidomimetic
inhibitor (SC-58272 [30]), and the … , selective inhibitors of Candida albicans myristoylCoA:protein …

… potent and selective peptidomimetic inhibitors have been developed by exploiting the differences
in peptide … A feature based pharmacophore for Candida albicans MyristoylCoA: protein …

… inhibitors have been reported: (a) peptidomimetic inhibitors [6… site 2 in N-Myristoyltransferase
binds with myristoyl-COA and … reported a pseudo-peptidic NMT inhibitor with an IC50 value …

… : myristoyl-CoA:protein N-myristoyltransferase (NMT).7 … peptide binding site is composed
by the C-terminal half.13 … 4, the potent and selective peptidomimetic NMT inhibitors could be …

… development of antifungal agents is Myristoyl-CoA:Protein … However the peptide and
peptidomimetic inhibitors of CaNmt… NMT as a target for cancer therapy is a new approach and lots …